DNA is the blueprint for life, but proteins carry out the essential functions in the cell.
Understanding the proteome, the complex collection of protein variants in our cells, is critical for unlocking the inner workings of biology and will enable us to develop a better understanding of human health and disease.
Evolved from the pioneering work from the Maglia Lab at the University of Groningen, our technology uses nanopores to detect and analyse single molecules with unparalleled sensitivity.
Nanopores are exquisite biosensors that capture and characterise protein or metabolite molecules. As these molecules move through the nanopore, they create unique electrical signatures that encode atomic-level differences.
Coupling our nanopore platform to state-of-the-art machine learning algorithms, we can decode the electrical signatures and reveal the molecule’s identity and detailed sequence information.
Real-time, rapid results to answer biological questions.
Any proteomic or metabolomic analysis, from short peptides to large proteins over 100 kDa.
See mutations and modifications in context with complete single-molecule profiling.
Cost-effective bench-top technology at the centre of your workflows.
Run any number of samples to meet the demands of both low- and high-volume labs.
Count molecules for naturally quantitative analyses.
Isoforms
Truncations
Mutations
Translation errors
Chirality
Quantitation
Synthesis
Degradation
Impurities
Phosphorylation
Glycosylation
Acetylation
Deamidation
Conjugation
Proteolysis
…and more
Portal’s instruments are available today through the protein characterisation services provided by our laboratories. We welcome opportunities for collaboration. Interested commercial or academic parties can also sign up for our Early Access Programme.
A range of bench-top instruments that bring state-of-the-art protein characterisation to the lab. Flexible solutions for everyone: academic research to biopharmaceutical and biotechnology, to industrial; small labs to high-volume workflows in service centres and core facilities.
Portal’s technology would not be possible without the incredible talent of our scientists, engineers and technicians. Supporting them is Portal’s executive team, who have over 50 years’ combined experience in biosensors and nanopore science.
If you’d like to find out more, have a general enquiry, would like to collaborate with us or sign up for Early Access, please get in touch by clicking the relevant button below:
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General EnquiriesMore InformationCollaborationsEarly AccessWe are dedicated to revolutionising the way we understand and manipulate proteins to drive advancements in human health, technology and biology.
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